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SMT C1100: Articles & Publications

There are a number of press articles and scientific publications about SMT C1100 and Duchenne Muscular Dystrophy and this section provides links to a selection of these.

Press Articles

Drug offers hope for treating muscular dystrophy
by BBC News

Utrophin drug shows promise for Duchenne and Becker muscular dystrophies
by the Muscular Dystrophy Campaign

Daily pill for Duchenne muscular dystrophy
by Oxford University

Daily treatment with SMT C1100 dramatically reduces muscular dystrophy symptoms in mdx mouse
by Action Duchenne, UK DMD charity

Scientific Papers

PLoS ONE
Daily Treatment with SMT C1100, a Novel Smally Molecule Utrophin Upregulator, Dramatically Reduces the Dystrophic Symptoms in the mdx Mouse
Jonathon M. Tinsley, Kay E. Davies et al.
Volume 6, Issue 4, May 2011

View the PLoS ONE paper

Journal of Medicinal Chemistry
Discovery of 2-Arylbenzoxazoles as Upregulation of Utrophin Production for the Treatment of Duchenne Muscular Dystrophy
Stephen P. Wren et al.
2011, 54 (9), pp 3241–3250

View the J. Med Chem paper

Bioorganic and Medicinal Chemistry Letters
Discovery and SAR of 2-arylbenzotriazoles and 2-arylindazoles as potential treatments for Duchenne muscular dystrophy
Stephen P. Wren et al.
Volume 21, Issue 16, 15 August 2011, Pages 4828-4831

View the BMCL paper