World Muscle Society Congress 2015 Presentations

Summit presented detailed results from the Phase 1b modified diet clinical trial of SMT C1100 for the treatment of DMD, as well as data from the broader utrophin modulation programme, at the 20th International Congress of the World Muscle Society held in Brighton, UK.

Copies of the presentations are available below for download:

Utrophin modulators to treat Duchenne Muscular Dystrophy: Results from a Phase 1b Clinical Trial of SMT C1100

Francesco Muntoni, Stefan Spinty, Helen Roper, Imelda Hughes, Valeria Ricotti, Bina Tejura, Gary Layton, Kay Davies and Jonathon Tinsley

Reporting detailed pharmacokinetic data from the Phase 1b modified diet trail of SMT C1100 in patients with DMD and outlining the plans for a Phase 2 proof of concept trial.


Development of an Automated Imaging Tool to Quantify regeneration in DMD Muscle Biopsies

Narinder Janghra, David J Elsey, Jennifer Morgan, Caroline Sewry, Francesco Muntoni, Kay E Davies and Jonathon Tinsley

Presentation on biomarker development to automate the quantification of muscle fibre regeneration in muscle biopsies from patients with DMD and Becker Muscular Dystrophy.